Postdoc in Circadian clocks & post-transcriptional gene regulation at the Gatfield lab, Center for Integrative Genomics, University of Lausanne, Switzerland
We are recruiting a postdoctoral researcher to study mechanisms of post-transcriptional gene regulation and their functional impact on the mammalian circadian system.
Our lab has a long-standing interest in combining fundamental research on RNA regulation with the discovery of mechanisms that control daily (“circadian”) rhythms in behaviour, physiology, metabolism and gene expression. In recent work, we have used in vitro, cellular and mouse models – as well as an array of biochemical and genomics methods – to explore, for example, the in vivo functions of the nonsense-mediated decay (NMD) pathway, the regulation of gene expression through upstream open reading frames (uORFs), or the role of ribosomal pausing as a novel regulatory mechanism.
In the proposed project, you will build on previous work from the lab to gain novel mechanistic and functional insights that are relevant to chronobiology and will also allow discovering fundamental principles of gene expression regulation. Moreover, we explicitly encourage applications from candidates who wish to bring in and develop a specific project of their own, in the broader area of RNA biology in mammals.
This position is fully funded; additional applications to personal international fellowships will be encouraged. The initial work contract is for the duration of one year, renewable 2 x 2 years, maximum of 5 years. Envisioned start date in position: as soon as possible / to be agreed.
You should hold a PhD degree in molecular biology, biochemistry, or a related discipline in the experimental life sciences; we expect full working proficiency in English and that you are a team player.
Our lab is located at the CIG at the University of Lausanne (UNIL), a vibrant, well-funded institute with a focus on functional genomics and equipped with modern core facilities (see www.unil.ch/cig). It is embedded in the broader Lausanne research environment that includes two universities (UNIL, EPFL), the Swiss Institute of Bioinformatics, Ludwig Center for Cancer Research, university hospital, and a cluster of biotech companies flourishing in the larger Lake Geneva area.
Our group is part of the National Centre of Competence in Research RNA & Disease (http://www.nccrrna- and-disease.ch). With this research initiative, Switzerland aims to strengthen and coordinate its activities in the rapidly evolving area of RNA biology and to obtain a leading position in the translation of knowledge from basic research into medically useful applications. You will benefit from NCCR networking and training opportunities throughout Switzerland and from contacts to other leading RNA research labs in Lausanne, Zürich, Bern, Basel and Geneva.
To apply, please submit a motivation letter describing why you are interested in joining our group, a CV (with copy of your PhD degree and a list of your scientific publications), and contact details for 2 or more referees via the UNIL website (offer 20755), or through the following URL:
For further information or informal requests please contact me at [email protected]